1. Signaling Pathways
  2. GPCR/G Protein
    Neuronal Signaling
  3. Melanocortin Receptor
  4. Melanocortin Receptor Inhibitors

Melanocortin Receptor Inhibitors

MC1R

MC3R

MC2R

MC4R

MC5R

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Sorry. There is currently no product that acts on isoform together.

Please try each isoform separately.

Melanocortin Receptor Inhibitors, Agonists & Antagonists
Product Name MC1R MC3R MC2R MC4R MC5R Purity
α-MSH      
MC4R
  99.57%
Melanotan I
MC1R
        99.75%
SHU 9119  
MC3R
 
MC4R
MC5R
99.95%
BMS-470539 dihydrochloride
MC1R
        99.95%
THIQ      
MC4R
  98.11%
Nonapeptide-1 acetate salt  
MC3R, Ki: 0.47 μM
 
MC4R, Ki: 1.34 μM
MC5R, Ki: 2.4 μM
98.70%
α-MSH TFA      
MC4R
  98.79%
MK-0493      
MC4R
  99.43%
Adrenocorticotropic Hormone (ACTH) (1-39), rat TFA    
MC2R
    99.84%
HS024 TFA      
MC4R
  99.80%
β-Melanocyte Stimulating Hormone (MSH), human TFA      
MC4R
  99.21%
CRN04894    
rat MC2R, Kb: 0.23 nM
MC2R, Kb: 0.34 nM
    98.41%
PF-00446687 free base      
MC4R
  98.47%
ML-00253764 hydrochloride      
MC4R
  99.47%
[D-Trp8]-γ-MSH  
MC3R
      99.57%
γ1-MSH  
MC3R
      99.71%
RO27-3225 TFA      
MC4R
  99.21%
Adrenocorticotropic Hormone (ACTH) (4-10), human      
MC4R
  99.23%
Resomelagon
MC1R
MC3R
      99.63%
γ-1-Melanocyte Stimulating Hormone (MSH), amide  
MC3R
      99.32%
β-Melanocyte Stimulating Hormone (MSH), human      
MC4R
  98.91%
PG106 TFA  
MC3R
      99.61%
ACTH (1-17) (TFA)
MC1R
        99.19%
HS014 TFA      
MC4R
  99.87%
CCZ01048 TFA
MC1R
        98.48%
hMC1R agonist 1
MC1R
       
JKC363      
MC4R
  99.55%
HS014      
MC4R
 
[D-Trp8]-γ-MSH TFA  
MC3R
     
Melanotan I acetate
MC1R
       
Agouti-related Protein (AGRP) (83-132) Amide (human)      
MC4R
 
α-MSH free acid  
MC3R, EC50: 0.16 nM
 
MC4R, EC50: 5.6 nM
 
Nonapeptide-1
MC1R, Ki: 40 nM
MC3R, Ki: 0.47 μM
 
MC4R, Ki: 1.34 μM
MC5R, Ki: 2.4 μM
99.04%
JKC363 TFA      
MC4R
 
γ1-MSH TFA  
MC3R
     
MSG606 TFA
MC1R